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. 2019 Jan 28;6(1):ENEURO.0401-18.2018. doi: 10.1523/ENEURO.0401-18.2018

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Copyright © 2019 Ignacio Pena-Bravo et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 3. — Effects of METH SA on eEPSCs. A, Female rats that self-administered METH had increased eEPSCs amplitude than saline control females; whereas there were no differences in males. B, Representative traces of eESPC’s amplitude. C, When analyzing the decay of eEPSCs, we found a significant interaction. In females the decay was not significantly different but in males, METH SA rats show a significantly faster decay than SAL counterparts (t test, p = 0.01). D, Analysis of the AUC also shows a significant interaction and a significant increase in the AUC of female METH SA rats. E, Representative traces showing the kinetics of eEPSCs. Each trace is the average of 10 events.