Table 3.
Variable | All patients n = 869 |
Hyperoxemia n = 199 |
Normoxemia n = 569 |
Hypoxemia n = 112 |
Hyper- and hypoxemia n = 11 |
---|---|---|---|---|---|
TWM-PaO2 | 14.0 (12.2–16.2) | 15.9 (14.1–18.2) | 13.8 (12.2–15.6) | 12.2 (10.7–14.0) | 13.90 (12.7–15.3) |
TWM-PaCO2 | 5.3 (4.9–5.7) | 5.3 (4.9–5.7) | 5.3 (4.9–5.7) | 5.4 (5.0–6.0) | 5.4 (5.2–5.6) |
PaO2 T-1 | 19.0 (12.1–33.8) | 52.7 (42.7–61.4) | 16.9 (12.1–24.5) | 9.6 (7.3–15.5) | 37.8 (20.3–49.8) |
PaO2 T0 | 17.1 (11.8–25.7) | 38.8 (21.2–52.9) | 16.0 (11.8–22.0) | 11.1 (8.4–16.5) | 41.5 (22.0–52.2) |
PaO2 T4 | 15.2 (12.2–19.7) | 16.5 (13.1–21.3) | 15.1 (12.4–19.6) | 12.4 (9.8–17.1) | 14.6 (11.1–17.8) |
PaO2 T12 | 13.2 (11.3–16.2) | 13.7 (11.5–16.6) | 13.2 (11.3–16.3) | 12.0 (10.3–14.9) | 11.7 (9.6–14.9) |
PaO2 T20 | 12.7 (11.0–15.1) | 12.9 (11.3–15.5) | 12.7 (11.0–15.0) | 12.1 (10.2–14.5) | 12.1 (10.0–15.0) |
PaO2 T28 | 11.9 (10.5–14.2) | 12.0 (10.4–13.9) | 12.2 (10.7–14.4) | 10.9 (9.7–13.5) | 10.9 (9.8–12.8) |
PaO2 T32 | 11.7 (10.4–13.7) | 11.7 (10.3–13.7) | 11.9 (10.6–13.8) | 10.8 (9.4–12.3) | 9.8 (8.2–11.4) |
PaO2 T36 | 11.3 (10.2–13.5) | 11.4 (10.2–13.5) | 11.5 (10.3–13.7) | 10.4 (8.9–11.8) | 9.2 (8.3–10.6) |
TWM pH | 7.35 (7.31–7.39) | 7.35 (7.32–7.39) | 7.35 (7.31–7.39) | 7.33 (7.28–7.37) | 7.35 (7.31–7.39) |
TWM PAW | 12.5 (10.3–16.6) | 12.6 (10.3–15.6) | 12.6 (10.2–16.9) | 11.9 (10.5–15.4) | 12.9 (11.1–14.2) |
TWM- BE | − 3.5 (−5.7 to − 1.5) | − 3.6 (− 5.9 to − 1.6) | − 3.6 (− 5.8 to − 1.5) | − 3.2 (− 5.2 to − 1.5) | − 3.65 (− 5.3 to − 2.2) |
TWM-FiO2% | 41.4 (34.9–49.7) | 39.2 (33.8–45.0) | 41.4 (34.7–49.4) | 47.9 (39.0–59.3) | 40.1 (34.3–50.6) |
TWM-PaO2/FiO2 | 35.1 (26.8–43.8) | 42.2 (34.2–50.0) | 34.1 (26.8–42.3) | 26.8 (20.4–34.7) | 34.4 (27.2–43.3) |
PaO2 arterial partial pressure of oxygen, PaCO2 arterial partial pressure of carbon dioxide. PaO2 and PaCO2 are displayed in kilopascal (kPa). Hyperoxemia PaO2 > 40 kPa, Hypoxemia PaO2 < 8 kPa, Normoxemia PaO2 values not defined hyper- or hypoxemia. TWM time weighted mean, PAW airway pressure, BE base excess, FiO2 fraction of inspired oxygen. Values are median with interquartile ranges (IQR). Patients exposed to hyper- and hypoxemia are also included in the separate hyperoxemia and hypoxemia exposure groups. T measuring time point in hours after inclusion into the TTM trial, T-1 first blood gas analysis after admission but before inclusion