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. 2019 Jan 28;19:24. doi: 10.1186/s12866-019-1393-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Genetic organization of type I-C and type II-A CRISPR/cas in 118 GAS strains. a cas genes are indicated in blue in type I-C and red in type II-A CRISPR/cas. Open diamonds and filled boxes indicate CRISPR repeats and spacers, respectively. b The distribution of 2 CRISPR types in 118 GAS strains represented in a Venn diagram. CRISPR, clustered regularly interspaced short palindromic repeats; GAS, Group A Streptococcus