Table 1.
Summary of 14 phage groups in the GAS strains
| Gp | Known virulence-related genes | Number of prophages | CDSs | Integration site | |
|---|---|---|---|---|---|
| min | max | ||||
| 1 | – | 4 | 17 | 56 | |
| 2 | – | 5 | 10 | 18 | |
| 3 | – | 10 | 22 | 97 | mutL |
| 4 | – | 38 | 13 | 57 | mutL |
| 5 | ssa, speC, speH, speI | 18 | 55 | 91 | dTDP-glucose-4,6,-dehydratase |
| 6 | – | 20 | 23 | 132 | |
| 7 | speA | 32 | 29 | 87 | tmRNA, recX, dTDP-glucose-4,6,-dehydrogenase |
| 8 | ssa, speC, speH, speI | 49 | 29 | 96 | DNA-binding protein HU |
| 9 | ssa, sda, speH, speI | 45 | 44 | 78 | tRNAser, dTDP-glucose-4,6,-dehydratase, Putative-gamma-glutamylkinase |
| 10 | speC, speK, slaA | 17 | 53 | 84 | tmRNA |
| 11 | speC, slaA, speK, speH, speI, ssa | 48 | 24 | 96 | Dipeptidase, tmRNA |
| 12 | sda, speC, slaA, speK | 47 | 21 | 130 | Dipeptidase, recX, Promoter of yesN |
| 13 | – | 3 | 61 | 69 | |
| 14 | speA, speC, ssa | 15 | 53 | 124 | CRISPR type II-A, RNA helicase |
CDS coding sequence, CRISPR clustered regularly interspaced short palindromic repeats, GAS Group A Streptococcus, Gp prophage group