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. 2019 Jan;60(1):117–127. doi: 10.1165/rcmb.2018-0105OC

Figure 2.

Figure 2.

YAP1 is required for endothelial cell (EC) sprouting in vitro. (A) Phase–contrast images showing EC sprouting from each bead in L-HMVE cells treated with angiopoietin (Ang) 1 or in combination with YAP1 siRNA, TEAD1 siRNA, Tie2 lentivirus, control siRNA with irrelevant sequences, or control virus (vector alone). Scale bar: 150 μm. (B) Graphs showing changes in sprout area (left) and length of the sprout (right) in L-HMVE cells treated with Ang1 or in combination with YAP1 siRNA, TEAD1 siRNA, Tie2 lentivirus, control siRNA with irrelevant sequences, or control virus (vector alone) (n = 3, *P < 0.05). Error bars represent SEM.