Fig. 2.

Effects of S42 or DHT on atrogin1, MuRF1, Igf1 expression on C2C12 myotubes. C2C12 myotubes were incubated with 1–10 µM of S42 or 100 nM of DHT or appropriate vehicle (DMSO) for 24 h. (A), (B), (C) Comparison of mRNA expression levels of atrogin1, MuRF1 and Igf1 relative to those of Gapdh, respectively are shown. Data are expressed as mean ± SE of triplicate samples. In statistical comparisons, the data of treated groups with DHT or S42 were compared with that of untreated group. *P < 0.05 vs DMSO by one-way ANOVA.