Table 2.

Respiratory and pertinent NICU care processes.

	Very preterm infants, < 33 weeks gestation				Extremely low birth weight infants, < 1000 g
Variable,	2008-2010	2011-2013	2014-2017	p	2008-2010	2011-2013	2014-2017	p
% or Median (IQR)	n = 229	n = 194	n = 217		n = 53	n = 52	n = 37
Delivery room intubation	23	15	5	<0.001†‡	64	40	19	<0.001∗†
Invasive ventilation	37	30	17	<0.001†‡	92	71	51	<0.001∗†
Invasive ventilation, days§	4 (1 - 20)	4 (1 - 13)	4.6 (2 - 16)	ns	18 (5 - 32)	9 (3 - 17)	15 (5 - 39)	ns
Non invasive mechanical ventilation (NIMV)	18	23	17	ns	58	65	65	ns
NIMV, days§	6 (3 - 15)	10 (2 - 17)	9 (2 - 24)	ns	8 (4 - 25)	10 (5 - 21)	19 (4 - 27)	ns
Continuous positive airway pressure (CPAP)	78	78	84	ns	89	83	81	ns
CPAP, days§	4 (2 - 19)	4 (2 - 16)	7 (2 - 21)	0.004†	22 (5 - 39)	25 (10 - 43)	30 (16 - 40)	ns
Surfactant	27	18	20	0.042∗	74	40	43	0.001∗†
Caffeine	48	58	69	<0.001†‡	85	94	97	ns
Vitamin A	15	1	13	<0.001∗‡	58	2	46	<0.001∗‡
Post natal steroids	10	7	3	0.01†	43	23	16	0.01†
Colostrum within 24 hours	45	76	86	<0.01∗†‡	38	72	84	<0.001∗‡
Infant antibiotics	67	59	41	<0.01†‡	96	90	73	0.004†

∗Statistically significant difference between 2008-2010 and 2011-2013.

†Statistically significant difference between 2008-2010 and 2014-2017.

‡Statistically significant difference between 2011-2013 and 2014-2017.

§Data summarized for those infants who received invasive ventilation, NIMV, CPAP, and nasal cannula.