Table 1.
Natural nutraceuticals along with mechanism.
| Nutraceuticals | Mechanism/activity |
|---|---|
| Proanthocyanidin (chestnut fruits) | Inhibit IL-8 secretion by impairing NF-kappa-B signaling [24] |
| Fish-based diet | Severe osteoarthritis and hip and elbow dysplasia [25] |
| Curcuma extract | Decrease the level of PSA for prostate cancer [26] |
| Supplementation of live yeast fostered | Regulate inflammation and epithelial barrier in the rumen and express DFEB1 coding for an antimicrobial peptide [27] |
| Inulin-type friction dietary fiber | Immune responses against hepatitis-B [28] |
| Bovine milk-derived oligosaccharide and B. lactis | Modulate gut microbiota and immune system [29] |
| Lipid-based nutrient supplements | Prevent growth faltering in infants [30] |
| Partially hydrolyzed cow's milk proteins | Cow's milk allergy in children [31] |
| Lactic acid bacteria (LAB) probiotic | Endometrial inflammation and infection [32] |
| Lipid-based nutrient supplement (LNS) | Moderate acute malnutrition (MAM) [33] |
| Vitamin D supplementation | Extraskeletal benefits [34] |
| Neutral amino acid supplements | Optimize neurocognitive function [35] |
| Myo-inositol | Gestational diabetes [36] |
| Lactobacillus fermentum CRL1446 | Enhances metabolism and oxidative parameters [37] |
| Dehydrozingerone and its dimer | Counteract the inflammation and oxidative stress [38] |
| 25-Hydroxy vitamin D | Cognitive status in older adults [39] |
| Malic acid, a precursor of citrate | Antioxidant activity [40] |
| Combined omega-3 fatty acids | Prevents atrophy in AD-related brain [41] |
| Lactobacillus rhamnosus SP1 | Insulin signaling and improves adult acne [42] |
| Omega-3 fatty acid ethyl esters | Breast cancer [43] |
| CoQ10 supplementation | Propofol inhibition on complex [44] |
| Omega-3 fatty acids and high-dose cholecalciferol | Type 1 diabetes [45] |
| Large neutral amino acid supplementation | Phenylketonuria (PKU) [46] |
| Low-fat yoghurt supplemented with a rooster comb extract | Muscle and joint function [47] |
| Lipid-based nutrient supplements | Home fortification in poor settings [48] |
| Cholecalciferol supplementation (HYPODD) | Arterial hypertension [49] |
| Omega-3 polyunsaturated fatty acid supplementation | Postmenopausal vascular disease [50] |
| Omega-3 fatty acids | Breast cancer prevention [51] |
| Myo-inositol supplementation | Gestational diabetes in obese pregnant women [52] |