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. Author manuscript; available in PMC: 2019 Jan 28.
Published in final edited form as: J Cell Biochem. 2018 Jul 16;119(11):8830–8840. doi: 10.1002/jcb.27133

Figure 6. Osteoblast-conditioned overexpression of Mdm2 increases the density and trabecular bone volume in the vertebra of adult mice.

Figure 6.

A. μCT images of vertebrae from 6-week and 9–11-month-old mice display marked differences in bone phenotype between wild type controls and Mdm2TgOb mice. B. Vertebral BV/TV. C. Vertebral Tb.N. D. Vertebral trabecular separation. E. DEXA measurements evaluating vertebral and whole body BMD demonstrate increases in BMD of Mdm2TgOb mice compared to wild type littermate controls. Data in all figures is presented as the average ± SEM. Asterisk signifies statistical significance at p<0.05.