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. Author manuscript; available in PMC: 2019 Oct 8.
Published in final edited form as: Cancer Cell. 2018 Oct 8;34(4):549–560.e9. doi: 10.1016/j.ccell.2018.08.019

KEY RESOURCES TABLE

REAGENT or RESOURCE SOURCE IDENTIFIER
Deposited Data
TCGA Affymetrix SNP6.0 array data The Cancer Genomics Cloud http://www.cancergenomicscloud.org/
TCGA whole exome sequencing data Genomic Data Commons https://portal.gdc.cancer.gov/
TCGA RNA sequencing data Genomic Data Commons https://portal.gdc.cancer.gov/
TCGA reverse-phase protein array (RPPA) data The Cancer Proteome Atlas
(http://tcpaportal.org/)
http://tcpaportal.org/tcpa/index.html
TCGA clinical data Genomic Data Commons https://portal.gdc.cancer.gov/
HapMap genotype data International HapMap Consortium
(ftp://ftp.ncbi.nlm.nih.gov/hapmap/)
ftp://ftp.ncbi.nlm.nih.gov/hapmap/genotypes/2010–05_phaseIII/hapmap_format/polymorphic/
HGDP genotype data The Human Genome Diversity
Project (http://www.hagsc.org/hgdp/)
http://www.hagsc.org/hgdp/files.html
1000 Genomes project data, phase 3 1000 Genomes project (http://www.internationalgenome.org/) ftp://ftp.1000genomes.ebi.ac.uk/vol1/ftp/release/20130502/
Cancer Cell Line Encyclopedia The Broad Institute https://portals.broadinstitute.org/ccle
The Genomics of Drug Sensitivity in Cancer
Project
The Wellcome Sanger Institute https://www.cancerrxgene.org/
Software and Algorithms
EIGENSTRAT 6.1.4 (Price et al., 2006) https://github.com/DReichLab/EIG
STRUCTURE 2.3.4 (Pritchard et al., 2000) http://web.stanford.edu/group/pritchardlab/structure.html
LAMP 2.5 (Sankararaman et al., 2008) http://lamp.icsi.berkeley.edu/lamp/
GISTIC 2.0 (Mermel et al., 2011) ftp://ftp.broadinstitute.org/pub/GISTIC2.0/
ABSOLUTE 1.0.6 (Carter et al., 2012) http://archive.broadinstitute.org/cancer/cga/absolute
HAPSEG 1.1.1 (Carter et al., 2011) http://archive.broadinstitute.org/cancer/cga/hapseg
deconstructSigs (Rosenthal et al., 2016) https://github.com/raerose01/deconstructSigs
R R https://www.r-project.org/about.html
HardyWeinberg R package https://cran.r-project.org/web/packages/HardyWeinberg/index.html
XML R package https://cran.r-project.org/web/packages/XML/index.html
vegan R package https://cran.r-project.org/web/packages/vegan/index.html
fGSEA R package https://bioconductor.org/packages/release/bioc/html/fgsea.html
ggplot2 R package https://cran.r-project.org/web/packages/ggplot2/index.html
GDC Data Transfer Tool Genomic Data Commons https://gdc.cancer.gov/access-data/gdc-data-transfer-tool
Other
RPPA features to PI3K pathway (Zhang etal., 2017) N/A
CIN70 signature (Carter et al., 2006) N/A
Relatedness among HapMap individuals (Pemberton et al., 2010) N/A
Relatedness among HGDP individuals (Rosenberg, 2006) N/A
TCGAA This paper http://52.25.87.215/TCGAA
CCGAA This paper http://52.25.87.215/CCGAA