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The expressions of TNF-alpha, IL-1 β , IL-6, VEGFA, and COX2 by immunohistochemistry in each group. Normal, normal group; CNP, chronic nonbacterial prostatitis group; Positive, estradiol induced CNP with testosterone; KRG (0.25g/kg), beta-estradiol induced CNP with KRG (0.25g/kg); KRG (0.5g/kg), estradiol induced CNP with KRG (0.5g/kg). ∗ P < 0.05, compared with the normal group, and # P < 0.05, compared with the CNP group.
