Overall study design and the measurements of metabolic traits in male and female offspring. (A) Framework of multiomics approaches to investigate the impact of prenatal BPA exposure. (B and C) Comparison of body weight, serum lipids, and glucose level in male mice between BPA and control groups at weaning age. (D and E) Comparison of body weight, serum lipids, and glucose level in female mice between BPA and control groups at weaning age. n = 9 to 13 mice (3 to 4 litters from different dams) per group. **P < 0.01; ***P < 0.001 by two-sided Student t test. FFA, free fatty acid; HDL, high-density lipoprotein; TC, total cholesterol; TG, triglyceride; UC, unesterified cholesterol.