Table 1.
Top 5 Human Traits for Which Associated Genes in GWAS Are Enriched for DMCs Across Adipose, Hypothalamus, and Liver at FDR <1% in MSEA
| Human Trait | Adipose |
Hypothalamus |
Liver |
|||
|---|---|---|---|---|---|---|
| P | FDR, % | P | FDR, % | P | FDR, % | |
| Obesity-related traits | 1.28E-16 | 0.00 | 3.03E-15 | 0.00 | 2.71E-19 | 0.00 |
| BMI | 1.30E-13 | 0.00 | 3.74E-07 | 0.00 | 9.66E-12 | 0.00 |
| Postbronchodilator FEV1/FVC ratio | 8.17E-09 | 0.00 | 1.45E-08 | 0.00 | 3.67E-07 | 0.00 |
| Type 2 diabetes | 1.21E-05 | 0.03 | 8.97E-09 | 0.00 | 0.001243 | 0.92 |
| Platelet distribution width | 8.16E-08 | 0.00 | 7.62E-05 | 0.16 | 5.20E-05 | 0.12 |
Abbreviations: FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.