Fig. 2.

Peptide modelling of 2 missense mutations in PCCA and PCCB genes; Arrows in A & B are showing predected active site (in red) in PCCA where A represent wild type PCCA and B represent PCCA with the mutation Gly142Asp. C is showing normal configration of PCCB while D is showing the configration with changing the amino acid Leu to His at position 388. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)