Figure 6.

Apl4 γ-ear causes effects similar to the loss of the Laa1–Laa2 complex. A, GFP-tagged WT or apl4-Δγear was imaged by fluorescence microscopy. B, IC₅₀ values for sertraline in indicated strains. C, IC₅₀ values for sertraline in indicated strains. For microscopy analysis, charts show the intensity of individual puncta, representative of three repeats. Bars indicate median and interquartile ranges. p values were determined by Mann–Whitney rank-sum analysis. Scale bars are 5 μm. For IC₅₀ values, charts show individual repeats. Bars indicate median and standard deviation. p values were determined by two-tailed Student's t test.