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. 2018 Dec 6;294(4):1240–1249. doi: 10.1074/jbc.RA118.006045

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© 2019 Patel et al.

Published by The American Society for Biochemistry and Molecular Biology, Inc.

Author's Choice—Final version open access under the terms of the Creative Commons CC-BY license.

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Figure 2. — Crystal structure of cIAP1R-UbcH5B–Ub-Ub^B complex. Shown is a cartoon representation of homodimeric cIAP1R-UbcH5B–Ub-Ub^B complex generated from crystallographic symmetry. The top and bottom panels are related by 90° rotation about the x axis. The two protomers of cIAP1R are colored green and orange. UbcH5B is shown in light blue, Ub^D in yellow, and Ub^B in wheat. Zn²⁺ ions are shown as gray spheres. UbcH5B–Ub linkage is shown in red and is indicated by arrows. cIAP1R's C-terminal tails are indicated by arrows.