Figure 1.

Average plasma concentrations of UPARANT after subcutaneous administration (20 mg/kg) to control (red dots and line) or STZ rats (black dots and line). Continuous lines correspond to the best fit of the equation C_t = C₀(e^−kelim∙t − e^−kabs∙t) where k_elim and k_abs correspond to the kinetic constants of the elimination and absorption phase, respectively. Values are expressed as means ± SD