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. Author manuscript; available in PMC: 2019 Jan 28.
Published in final edited form as: J Steroid Biochem Mol Biol. 2017 Feb 13;173:273–279. doi: 10.1016/j.jsbmb.2017.02.003

Table 3:

The effect of vitamin D deficiency* on placenta gene expression (ΔCT).

Vitamin D deficient at V1 Median(IQR) Vitamin D sufficient at V1
Median(IQR)
p-value Vitamin D deficient at V6/7 Median(IQR) Vitamin D
sufficient at V6/7 Median(IQR)
p-value
VEGF 3.1(2.2,4.0) 4.3(3.6,5.0) 0.068 2.7(2.2,3.0) 3.6(2.9,4.6) 0.014
PGF −3.5(−4.0,−2.4) −2.3(−2.6,−0.5) 0.056 −3.4(−4.0,−2.9) −2.8(−3.9,−1.7) 0.191
sFlt-1 −3.6(−4.0,−2.5) −1.6(−2.5,−1.2) 0.010 −3.7(−4.1,−3.6) −2.7(−3.6,−1.9) 0.008
PRB 7.8(6.7,9.0) 10.0(9.2,10.7) 0.021 7.3(6.5,8.5) 8.7(7.1,9.5) 0.113
ESR1 7.9(7.4,8.5) 9.4(8.3,10.0) 0.069 7.6(6.8,8.3) 8.3(7.5,9.3) 0.061
hCGb −6.3(−7.6,−5.5) −4.5(−5.9,−3.8) 0.065 −6.4(−7.2,−6.0) −5.9(−7.6,−4.6) 0.355
hPL −14.4(−14.9,−13.3) −13.4(−13.8,−12.7) 0.031 −13.7(−14.6,−13.4) −14.2(−14.9,−13.2) 0.509
CYP24A1 5.6(4.5,6.3) 7.0(5.3,7.5) 0.237 5.6(5.0,6.4) 5.8(4.7,7.0) 0.765
CYP27B1 7.7(6.8,8.5) 8.3(8.0,10.0) 0.097 7.6(6.7,8.4) 8.1(7.0,9.0) 0.451
GRα 0.6(−0.5,1.2) 2.0(1.8,2.2) 0.022 0.2(−1.3,1.1) 1.0(−0.1,2.0) 0.128
VDR 7.4(6.9,8.4) 8.6(7.3,8.9) 0.236 7.2(7.1,8.2) 7.7(6.9,8.5) 0.853
*

25(OH)D<100nmol/L