Table 1.

Comparison of the Clinical-Pathological Characteristics of the Breast Tumor Cohorts.

	Total (n=768)		ER+ (n=447)		ER−, Nonbasal (n=193)		ER−, Basal (n=128)		P Value
Patient age
Median	65		68		56		57.5
Tumor grade	# cases	%	# cases	%	# cases	%	# cases	%
0-5	34	6	21	6	9	7	4	8	<.0001
6-7	362	66	298	82	53	39	11	23
8-10	151	28	44	12	74	54	33	69
Nodal status
+ve	356	46.8%	204	45.6%	92	48.8%	60	48.4%	.7275
−ve	404	53.2%	243	54.4%	98	51.2%	63	51.6%
Tumor size
>2.5 cm	301	48%	195	45%	26	50%	80	56%	.0589
<=2.5 cm	331	52%	242	55%	26	50%	63	44%
Claudin 1 (H-score)	# cases	median	# cases	median	# cases	median	# cases	median	<.0001
	643	30	371	15	164	70	108	62.50
PKCα (intensity)	# cases	%	# cases	%	# cases	%	# cases	%
1	387	73.6%	307	73.6%	31	77.5%	49	71.0%	.7595
2, 3	139	26.4%	110	26.4%	9	22.5%	20	29.0%
PKCε (intensity)	# cases	%	# cases	%	# cases	%	# cases	%
1	449	69.0%	259	64.9%	112	71.8%	78	81.3%	<.01
2, 3	202	31.0%	140	35.1%	44	28.2%	18	18.8%
Recurrence (5 years)		32.0%		22.8%		50.3%		37.5%	<.001
Survival (5 years)		76.5%		89.0%		54.5%		65.4%