Table 3.

Patient Survival/Recurrence Related to Claudin 1 and PKCε Levels

		5-Year Survival/Recurrence				20-Year Survival/Recurrence
		Total	ER+	ER− Nonbasal	ER− Basal	Total	ER+	ER− Nonbasal	ER− Basal
Claudin 1 (H-score >40 vs. H-score ≤40)	n=	643	371	164	108	643	371	164	108
Survival		1.46⁎	NS	NS	NS	NS	NS	NS	NS
Recurrence		NS	NS	NS	NS	NS	NS	NS	NS
Survival or recurrence		NS	NS	NS	NS	NS	NS	NS	NS
PKCε intensity (2, 3, vs. 1)	n=	685	399	172	114	685	399	172	114
Survival		1.38⁎	NS	1.79⁎	2.35⁎⁎	NS	NS	1.79⁎⁎	2.02⁎
Recurrence		NS	NS	1.80⁎	2.12⁎	NS	NS	1.96⁎	NS
Survival or recurrence		NS	NS	1.76⁎⁎	2.33⁎⁎	NS	NS	1.91⁎⁎	NS

Claudin 1 was not a prognostic indicator of disease recurrence/survival; however, high PKCε was associated with shorter survival in patients with ER− tumors. Values are hazard ratios. NS, not statistically significant.

^⁎P<.05.

^⁎⁎P<.01.