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. 2018 Dec 30;23(2):1541–1552. doi: 10.1111/jcmm.14062

Figure 7.

Figure 7

The mechanism of miR‐552 on altering HCC cell behaviours. Overexpression of miR‐522 binds to AJAP1 mRNA and inhibits its translation. As a result, the level of AJAP1 protein was attenuated, and the level of Src protein, which suppressed by AJAP1, was elevated. The downstream pathway was activated and further promoted EMT progression and cell proliferation. The highlighted elements of the model were verified in our study