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. Author manuscript; available in PMC: 2019 Jan 28.
Published in final edited form as: J Control Release. 2013 Sep 25;172(3):1151–1160. doi: 10.1016/j.jconrel.2013.09.016

Figure 5.

Figure 5

In vivo persistence of the peptide nanotubes after intravitreal injection in rats. (a) Confocal microscopic image of Alexa-488 labeled pazopanib-dipeptide nanotubes. (b) Intravitreal fluorescence profile of pazopanib-dipeptide nanotubes. (c) Peak fluorescence values of pazopanib-dipeptide nanotubes in the intravitreal space at different time points. Fluorescence values determined using fluorophotometry after administration of Alexa 488-labeled pazopanib loaded dipeptide nanotubes in rats by intravitreal injections. 5 µl of nanosystem formulation was injected per eye and fluorescence readings were taken at different time points using Flurotron Master. The data is expressed as mean ± SD; n= 3 eyes.