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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: MRS Commun. 2018 Jul 13;8(3):642–651. doi: 10.1557/mrc.2018.120

Figure 1.

Figure 1

Schematic work flow explaining the concept of rGO mediated fluorescence quenching concept measures the miRNA hybridization associated fluorescence recovery: (i) Cy5-antimiR-21, (ii) rGO in contact with Cy5-antimiR-21 quenches fluorescence through strong electrostatic proximity binding with hydrogen bonds, (iii) hybridization of miR-21 to Cy5-antimiR-21 releases miR-antimiR hybrid and recovers fluorescence signal, and (iv) graph showing the theoretical fluorescence signal expected at different stages of this work flow.