Table 2. sAPE1 level and its association with clinical and pathological characteristics of the HCC group.

sAPE1 (pg/mL)
	Count	Median (95% CI)	p value
Age			ns
<72	52	74.2 (60.5–96.4)
>72	47	78.8 (66.2–103.7)
Sex			ns
Male	77	73.9 (63.2–87.2)
Female	22	97.1 (65.0–122.9)
Etiology			<0.001
Alcohol metabolic	54	62.6 (48.6–73.9)
Alcohol metabolic viral	18	132.37 (84.3–208.2)
Viral	23	98.8 (85.4–141.1)
Other*	4	63.2
CTP			ns
A	73	78.8 (65.0–96.4)
B/C	23	70.76 (44.5–128.6)
BCLC			ns
0-A	65	77.3 (60.5–96.4)
B-C-D	32	74.5 (48.6–101.3)
GRETCH			<0.05
Low	15	60.5 (33.0–101.3)
Intermediate-high	68	83.2 (68.1–91.1)
CLIP			ns
0–1	59	78.7 (67.3–97.7)
2–3–4	25	71.6 (56.1–114.7)
ITA.LI.CA prognostic			ns
2	44	87.1 (69.7–107.8)
3	21	74.6 (56.1–108.7)
4	12	53.5 (32.3–159.2)
5–8	7	71.6 (40.3–138.3)
Number of lesions			ns
Single <2 cm	15	86.9 (43.8–120.4)
Single or 3 <3 cm	46	74.6 (60.5–117.9)
Large-single or multi	37	74.5 (61.2–89.5)
AFP			ns
<20 ng/mL	52	76.7 (65–87.2)
20–400 ng/mL	13	138.3 (37.1–179.9)
>400 ng/mL	12	80.5 (43.8–122.9)