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. Author manuscript; available in PMC: 2020 Feb 25.
Published in final edited form as: J Perinat Med. 2019 Feb 25;47(2):222–240. doi: 10.1515/jpm-2018-0216

Table 5.

Birthweight below the 50th percentile, small-for-gestational-age neonate, birthweight-to-placenta-weight and mean amniotic fluid concentrations of erythropoietin (EPO), cardiac troponin I (cTnI), and glial fibrillary acidic protein (GFAP) according to the pattern of raised amniotic fluid concentration of EPO in cases of fetal death

Raised
EPO only
(n=5)
Raised
EPO and cTnI
(n=23)
Raised
EPO and GFAP
(n=8)
Raised
EPO, cTnI
and GFAP
(n=19)
P-valuea
Birthweight <50th centile 4 18/21 6 15 0.87
Small-for-gestational-age neonate 1 10/21 2 5 0.47
Birthweight-to-placenta-weight ratio 4.95 3.75 4.35 3.68 0.40
Mean amniotic fluid concentration
 EPO (mIU/mL) 27.24 226.93 261.62 724.30 0.41
 cTnI (pg/mL) 67.27 232.48 70.93 380.38 <0.001
 GFAP (ng/mL) 1.1 1.65 3.66 4.24 <0.001
a

Kruskal-Wallis test for continuous variables and exact tests for categorical variables.