Table 6:
Prognostic factors of visual outcome ≤ 20/200 of microbial keratitis cases from Saint Louis (1999–2013)
| All Cases (N=140) | Univariate logistic regression | Multivariate logistic regression | ||||
|---|---|---|---|---|---|---|
| Prognostic factors | OR | 95% CI | p-value# | OR | 95% CI | p-value |
| Age ≥ 60 years | 2.99 | 1.25–7.18 | .098 | 3.11 | 1.23–7.89 | .017 |
| Large ulcers > 5 mm | 2.99 | 1.25–7.18 | .098 | 3.63 | 1.42–9.26 | .007 |
| Pseudomonas sp. | 0.80 | 0.33–1.90 | 1 | |||
| Fungi/acanthamoeba | 0.97 | 0.33–2.87 | 1 | |||
| Tertiary referred cases | 0.73 | 0.32–1.66 | 1 | |||
| Prior ophthalmic steroid use | 2.41 | 0.97–5.96 | .406 | 2.44 | 0.92–6.49 | .072 |
| Co-morbid ocular conditions§ | 2.94 | 1.29–6.70 | .070 | |||
| Bacteria-only cases (N=117) | ||||||
| Age ≥ 60 years | 3.19 | 1.25–8.17 | .09 | 3.63 | 1.35–9.78 | .011 |
| Large ulcers > 5 mm | 3.44 | 1.33–8.86 | .066 | 3.89 | 1.44–10.53 | .008 |
| Pseudomonas ps. | 0.77 | 0.31–1.92 | 1 | |||
| Tertiary referred cases | 0.59 | 0.23–1.55 | 1 | |||
| Prior ophthalmic steroid use | 2.44 | 0.89–6.70 | .492 | |||
| Co-morbid ocular conditions§ | 3.23 | 1.32–7.94 | .066 | |||
OR = odds ratio
CI = confidence interval
#
Bonferroni corrected p-values
§
Including prior ophthalmic surgery and pre-existing ocular surface disease