Table 4.
Evidence level for VD Association with Knee OA.
| Association of VDD to OA knee | Study | Effective Evidence level | Types of studies | |
|---|---|---|---|---|
| SOA prevalence | Questionnaire | Muraki S et al + Heidari et al + Mohamed A.Abu + |
Moderate (4+) | 1case control/3cross-sectional) |
| KSS score | Ja jenson et al + | |||
| ROA Prevalence | KL | Muraki S et al(-) | Limited 1- | cross-sectional study |
| Osteophytes | Ding C. et al(-) | limited 1- | cross-sectional study | |
| JSN | Ding C. et al(+) | limited1+ | cross-sectional study | |
| ROA Incidence | KL | Berginik AP. et al(-) Mc Alindon et al(-) |
Moderate 2- / | 1Cohort study 1RCT |
| JSN | Bergnik AP. et al (+) | Limited 1+ | Cohort study | |
| Distal femoral cartilage thickness | Ultrasonography | Fevziye Ünsal Malas et al (+) | Limited 1+ | retrospective study |
| ROA Progression | KL | Bergnik AP. et al (+) Mc Alindon et al (+) |
Moderate (2+ | 1Cohort 1RCT |
| Osteophytes | Mc Alindon et al (+) Felson DT. et al (Framingham)(-) Felson DT et al (BOKS) (-) |
Conflicting (2-and 1+)) | Cohort studies | |
| JSN | Fang fang et al (+) | Limited 1+ | Cohort studies | |
| cartilage defect Progression | Felson DT et al BOKS (-) Ding C. et al(-) |
Moderate 2- | Cohort studies | |
| cartilage volume loss Progression | Ding C. et al(+) | 1+ | Cohort studies |