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. 2019 Jan 22;9:7. doi: 10.3389/fonc.2019.00007

Table 1.

Mean and standard deviation values of per-target paired CI/GI difference between different planning techniques.

HD MLC non-coplanar VMAT HD MLC coplanar VMAT Halcyon MLC V1 coplanar VMAT Halcyon MLC V2 coplanar VMAT
(A) CI difference (top - left) for targets with diameter < 1 cm
HD MLC non-coplanar DCA −0.112 ± 0.276 (p = 0.014) –0.016 ± 0.294 (p = 0.637) 0.226 ± 0.363 (p < 0.001) 0.089 ± 0.284 (p = 0.044)
HD MLC non-coplanar VMAT 0.096 ± 0.260 (p = 0.065) 0.338 ± 0.381 (p < 0.001) 0.200 ± 0.300 (p < 0.001)
HD MLC coplanar VMAT 0.242 ± 0.241 (p < 0.001) 0.105 ± 0.185 (p < 0.001)
Halcyon MLC V1 coplanar VMAT −0.137 ± 0.232 (p < 0.001)
(B) CI difference (top - left) for targets with diameter > 1 cm
HD MLC non-coplanar DCA −0.194 ± 0.149 (p < 0.001) -0.193 ± 0.13 (p < 0.001) −0.129 ± 0.164 (p < 0.001) −0.154 ± 0.148 (p < 0.001)
HD MLC non-coplanar VMAT 0.001 ± 0.135 (p = 0.596) 0.065 ± 0.149 (p = 0.002) 0.040 ± 0.135 (p = 0.084)
HD MLC coplanar VMAT 0.064 ± 0.095 (p < 0.001) 0.039 ± 0.093 (p = 0.016)
Halcyon MLC V1 coplanar VMAT –0.025 ± 0.074 (p = 0.082)
(C) GI difference (top - left) for targets with diameter < 1 cm
HD MLC non-coplanar DCA −1.12 ± 2.80 (p = 0.004) 0.34 ± 4.71 (p = 0.220) 1.76 ± 4.34 (p < 0.001) 1.52 ± 3.66 (p < 0.001)
HD MLC non-coplanar VMAT 1.46 ± 3.53 (p < 0.001) 2.88 ± 3.23 (p < 0.001) 2.641 ± 2.66 (p = 0.001)
HD MLC coplanar VMAT 1.41 ± 3.03 (p = 0.002) 1.18 ± 4.06 (p = 0.020)
Halcyon MLC V1 coplanar VMAT −0.24 ± 2.543 (p = 0.136)
(D) GI difference (top - left) for targets with diameter > 1 cm
HD MLC non-coplanar DCA −0.66 ± 0.95 (p < 0.001) 0.62 ± 1.17 (p < 0.001) 0.73 ± 0.8896 (p < 0.001) 0.66 ± 0.9276 (p < 0.001)
HD MLC non-coplanar VMAT 1.28 ± 1.146 (p < 0.001) 1.39 ± 1.007 (p < 0.001) 1.32 ± 0.8818 (p < 0.001)
HD MLC coplanar VMAT 0.11 ± 0.906 (p = 0.350) 0.04 ± 1.075 (p = 0.200)
Halcyon MLC V1 coplanar VMAT –0.06 ± 0.623 (p = 0.810)
Bold indicates statistical significance based on Wilcoxon Signed-Rank Test

Values shown were generated using CI and GI from the corresponding technique indicated in the top row minus the technique indicated in the left-most column. Positive mean values in the table cells indicate that the corresponding technique in the top row produced on average a higher CI or GI compared to the corresponding technique in the first column on the left; and negative values indicate the opposite. Bold text indicates statistical significance found between the corresponding techniques using Wilcoxon Signed Rank test.