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. 2018 Oct 10;49(1):95–108. doi: 10.1007/s40279-018-0994-1

Table 1.

LL-BFR training and changes in muscle strength

Study Subjects Protocol N Exercise mode Duration/frequency Strength measurement Percentage increase Conclusion
Cook et al. [81] Older adults (≥ 65 y)

LL-BFR (30–50% 1RM)

HL (70% 1RM)

12

12

Leg curl

Leg extension

Leg press

12 wk; 2 days/wk

Isometric leg extension

Dynamic leg curl

Dynamic leg extension

Dynamic leg press

LL-BFR: 10–26%

HL: 18–56%

No significant between-group differences except for dynamic leg extension (greater in HL)
Karabulut et al. [4] Older men (50–64 y)

LL-BFR (20% 1RM)

HL (80% 1RM)

13

13

Leg press

Leg extension

6 wk; 3 days/wk

Dynamic leg press

Dynamic leg extension

LL-BFR: 19%

HL: 20–31%

No significant between-group differences except for dynamic leg extension (greater in HL)
Libardi et al. [82] Older adults (> 60 y)

LL-BFR (20–30% 1RM)

HL (70-80% 1RM)

10

8

Leg press 12 wk; 2 days/wk Dynamic leg press

LL-BFR: 35%

HL: 38%

No significant between-group differences
Patterson and Ferguson [83] Older adults (62–73 y)

LL-BFR (25% 1RM)

LL (25% 1RM)

10

10

Plantar-flexion 4 wk; 3 days/wk

Isokinetic plantar flexion

    0.52; 1.05; 2.09 rad/s

Isometric plantar flexion

Dynamic plantar flexion

LL-BFR: 11–20%

LL: 0–4%

Greater strength improvements for LL-BFR except for isokinetic torque at 1.05 rad/s and 2.09 rad/s
Shimizu et al. [84] Older adults (> 65 y)

LL-BFR (20% 1RM)

LL (20% 1RM)

20

20

Leg extension

Leg press

Rowing

Chest press

4 wk; 3 days/wk

Dynamic leg extension

Dynamic leg press

Dynamic rowing

Dynamic chest press

LL-BFR: 6–19%

LL: − 2 to 7%

No significant between-group differences
Thiebaud et al. [85] Older women (61 ± 5 y)

LL-BFR (10–30% 1RM)

HL (70–90% 1RM)

6

8

Seated chest press

Seated row

Seated shoulder press

8 wk; 3 days/wk

Dynamic chest press

Dynamic row

Dynamic shoulder press

LL-BFR: 4–10%

HL: 5–18%

No significant between-group differences
Vechin et al. [86] Older adults (59–71 y)

LL-BFR (20–30% 1RM)

HL (70–80% 1RM)

8

8

Leg press 12 wk; 2 days/wk Dynamic leg press

LL-BFR: 17%

HL: 54%

HL tends to result in greater strength increases
Yasuda et al. [33] Older women (61–86 y)

LL-BFR (35–45% 1RM)

HL (70–90% 1RM)

10

10

Squats

Knee extension

12 wk; 2 days/wk

Isometric knee extension

Isometric knee flexion

Dynamic leg press

Dynamic knee extension

LL-BFR: 7–17%

HL: 4–18%

Significant increase in LL-BFR group, no significant increase in HL group

1RM one-repetition maximum, CON control group, HL high-load, LL low-load, LL-BFR low-load blood flow restriction, wk week/s, y years