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. 2019 Jan 28;9:797. doi: 10.1038/s41598-018-37545-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparisons of three Subtypes on disease progression of the variable MDS-UPDRS Part I-III, and H&Y. The time interval between baseline and follow-up is 6 years. The larger slope illustrates a more rapid progression on the corresponding variables. The filled regions indicate 95% Confidence Intervals as error bars for corresponding point estimates. Variables with the p-value < 0.05 are shown.