Figure 4.

Comparing Gaussian Curvature (K) heat maps for different representative primary cilia across all conditions. (a) WT_SAG cells exhibit a cylindrical structure with a hemispheric cap. (b) $W{T}_{SAG}^{cb}$ cells are shown to have a severe narrowing region near the tip of the cilium, denoted by black arrows that highlight the red, negative K regions. (c) IFT25_NoAg cells also show narrowing near the tip, whereas interestingly, (d) IFT25_SAG cells had narrowing closer to the base of the primary cilium in a few cells. Heat maps are all on the same scale. Scale bars, 0.5 μm. To see this figure in color, go online.