Figure 2.

Mean RMSF in (A) C_α positions and (B) side-chain centroids for SCR7^Y402 (blue) and SCR7^H402 (red) are shown for each residue position in SCR7. Shaded regions correspond to one standard deviation above and below the mean RMSF values. Circles are placed in RMSF plots to denote the location of residues Y390, [Y/H]402, R404, K405, F406, K410, D413, V414. Greater differences in RMSF between SCR7 isoforms are observed in C_α positions than in side-chain centroids. Additionally, the Y402H polymorphism is associated with increased RMSF for residues proximal to position 402. To see this figure in color, go online.