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. 2019 Jan 25;39(1):BSR20181804. doi: 10.1042/BSR20181804

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© 2019 The Author(s).

This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY).

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FBXL19-AS1 is up-regulated in lung cancer tissues and cell lines and relates to poor prognosis of patients

(A) RT-qPCR results showed that expression of FBXL19-AS1 was higher in tumor tissues than in adjacent non-tumor tissues. (B) RT-qPCR results showed that expression of FBXL19-AS1 was higher in lung cancer cell lines (A549, H1299, H1975, H125, and SPC-A-1) than in normal human lung cells (MRC-5). (C) Relative FBXL19-AS1 expression levels in different clinical stages (I-II and III-IV). (D) Kaplan–Meier curve and the log-rank test showed that the expression of FBXL19-AS1 was associated with overall survival in patients with lung cancer. Error bars represent the mean ± SD of at least three independent experiments. **P<0.01 versus control group.