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. 2018 Sep 9;16:40–52. doi: 10.1016/j.jot.2018.08.003

Table 2.

Modified O`Driscoll histological score.

Characteristic Grading Score
I. Nature of predominant tissue Hyaline cartilage 4
Mostly hyaline cartilage 3
Mixed hyaline and fibrocartilage 2
Mostly fibrocartilage 1
Some fibrocartilage, mostly nonchnodrocytic cells 0
II. Structural characteristics
A. Surface irregularity Smooth and intact 3
Superficial horizontal lamination 2
Fissures 1
Severe disruption, including fibrillation 0
B. Structural integrity, homogeneity Normal 2
Slight disruption, including cysts 1
Severe disintegration, disruptions 0
C. Thickness 100% of normal adjacent cartilage 2
50–100% or thicker than normal 1
0–50% of normal cartilage 0
D. Bonding to adjacent cartilage Bonded at both ends of graft 2
Bonded at one end or partially both ends 1
Not bonded 0
III. Freedom from cellular changes of degeneration
A. Hypocellularity Normal cellularity 2
Slight hypocellularity 1
Moderate hypocellularity, or hypercellularity 0
B. Chondrocyte clustering No clusters 2
<25% of the cells 1
25–100% of the cells 0
IV. Freedom from degenerate changes in adjacent cartilage Normal cellularity, no clusters, normal staining 3
Normal cellularity, mild clusters, moderate staining 2
Mild or moderate hypo/hypercellularity, slight staining 1
Severe hypocellularity, poor or no staining 0
V. Subchondral bone
A. Reconstruction of subchondral bone Normal 3
Reduced subchondral bone reconstruction 2
Minimal subchondral bone reconstruction 1
No subchondral bone reconstruction 0
B. Inflammatory response in subchondral bone region None/mild 2
Moderate 1
Severe 0
VI. Safranin O staining Normal or near normal 3
Moderate 2
Slight 1
None 0
Total, max 28