Table 5.

Gene–environment interactions and EH risk model analysis results

Model	Bal. Acc. CV Training	Bal. Acc. CV Testing	CV consisitency	χ2 value	P value	OR (95% CI)
Alcohol	0.675	0.671	7/10	137.251	<0.001	9.668 (6.315–14.803)
Alcohol history	0.675	0.670	6/10	131.321	<0.001	9.542 (6.102–12.548)
Alcohol, rs6435156, rs397514716	0.678	0.687	10/10	132.444	<0.001	8.088 (5.481–11.934)
BMI, alcohol, rs6435156, rs397514716	0.618	0.620	6/10	130.69	<0.001	7.284 (5.050–10.506)
Gender, BMI, alcohol, rs6435156, rs397514716	0.585	0.591	5/10	121.011	<0.001	6.658 (4.718–9.396)
Gender, BMI, alcohol, rs6435156, rs121909287, rs397514716	0.594	0.549	4/10	120.017	<0.001	5.699 (4.177–7.775)
Gender, BMI, alcohol, age, rs6435156, rs1048829, rs121909287	0.603	0.5033	4/10	127.882	<0.001	5.737 (4.244–7.755)
Gender, BMI, alcohol, age, rs6435156, rs1048829, rs121909287, rs397514716	0.611	0.4696	6/10	147.524	<0.001	6.061 (4.487–8.187)

Alcohol history is indicated by “1,” No alcohol history “2”; BMI: ≥ mean is indicated by “1,” < mean “2”; Gender: Male “1,” Female “2.” Age: ≥ mean is indicated by “1,” < mean “2”; Hypertension history: Yes is “1,” No is “2.”