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Overview of the main system-level modules in the iAPS. The smartphone client app communicates with the CGM and pump hardware devices, interfaces with algorithm modules CLC, IOB, MCC, and HMS (which can also interface with each other), and securely stores data in a local database and a remote server accessible to clinicians in real time through a monitoring site. CLC, closed-loop-controller; HMS, health monitoring system; MCC, meal-correction-controller.
