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ATAD2 is the direct target of miR-372 in RCC. (A) The putative binding sites of miR-372 in the ATAD2 3′-UTR. (B) The luciferase activities of the ATAD2 3′UTR was detected by luciferase reporter gene assays in RCC cells which were cotransfected with wild-type ATAD2 3′UTR or mutational type ATAD2 3′UTR and miR-372 mimics, respectively. (C) ATAD2 expression in 786-O treated with miR-372 mimics. (D) ATAD2 expression in Caki-1 treated with miR-372 inhibitor. *P<0.05.
