Fig. (3).

Relative expression of genes involved in ATRA metabolism in HepG2/C3A cells and HT-29 after 12 hours of exposure to genistein at 5 or 50 µM. Values are the mean ± standard deviation of three independent experiments. Asterisks (*) indicate statistically significant differences (p<0.05); (**) indicate statistically significant differences (p<0.01) and (***) indicate statistically significant differences (p<0.005) between the treated genistein groups and the control without genistein group, according to the REST software 2009. Normalized data with GAPDH.