Fig. (1).

Illustration of early neurological deterioration models: infarct swelling (A), small subcortical infarct (B), mismatch (C) and recurrence (D). END A represents brain swelling of a large acute infarction and the final infarction may exceed the area of oligemia due to edematous swelling of infarction tissue itself. END B shows small subcortical infarct and the END is due to the transformation of non-core hypoperfused area into infarction in the anatomy of corticospinal tracts. END C demonstrates the perfusion-diffusion mismatch concept and the END is related to the extension of infarction into a previously oligemic area. END D reveals a new ischemic area in a previously healthy area.