Table 2.
Perfusion-diffusion mismatch in prediction of early neurological deterioration.
| Predictor | Number | Image Time | END |
Sensitivity/
Specificity/PPV/NPV |
Odds Ratio (95% Confidence Interval); P Value | Study |
|---|---|---|---|---|---|---|
| (Tmax>4s – DWI) >10ml | 137 | <24 hours | Any clinical deterioration | 77%/ 83%/ NA/ NA | NA | Asdaghi et al. [16] |
| (Tmax>6s/DWI) > 120% DWI < 100ml |
49 | <24 hours | NIHSS≧4 in 72 hours | 80%/ 79.5%/ NA/ NA | 17.0 (2.8~105.0); p<0.01 | Hsu et al. [17] |
| (Tmax>6s/DWI) > 120% + (Tmax>6s) > 10ml |
464 | <4.5 hours | NIHSS≧4 in 24 hours | 60%/ 67% / 9.4%/ 96.7% | NA | Simonsen et al. [18] |
| (Tmax>6s) > 35ml | 76%/ 70.4%/ 12.8%/ 98.1% | NA |
Abbreviations: DWI: Diffusion Weighted Imaging; END: Early Neurological Deterioration; NA: Not Available; NIHSS: National Institutes of Health Stroke Scale; NPV: Negative Predictive Value; PPV: Positive Predictive Value; Tmax: Time to Maximum of Residual Tissue.