Table 3.
Risk of adverse neuro-developmental outcomes in children < 10 years of age born with low birth weight compared to those born with normal birth weight
| Outcomes | No. of studies | No. of subjects | Age range | Pooled RR (95% CI) | I 2 Statistic |
|---|---|---|---|---|---|
| Low cognitive scorea | 4 | 584 | < 10 years | 2.69 (1.34, 5.39) | 12.7% |
| Motor impairmentb | 3 | 312 | < 10 years | 3.32 (1.56, 7.06) | 0.0% |
| Developmental delayc | 3 | 693 | ≤3 years | 1.97 (1.41, 2.73) | 69.3% |
aDefined as mental quotient of < 85 or IQ score ≤ 25th percentile
bdefined as either presence of signs of motor dysfunction on clinical examination or motor quotient of < 85
cdefined as developmental quotient of < 60 on developmental screening tools and/or presence of visual/hearing/speech difficulties