Fig. 2.

Clustering of the 596 most differently abundant proteins between ulcerative colitis (UC) and healthy controls. a Hierarchical clustering reveals three main protein clusters. Low abundances are indicated in blue, high abundances in red. b Protein abundance profiles of the three main clusters. 1: minor cluster of 20 proteins (including calprotectin) with increased abundance in UC, with a subgroup of UC samples showing a more pronounced increase. 2: major cluster of 247 proteins with increased abundance in UC. 3: Cluster of 313 proteins with a decreased abundance in UC