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. 2019 Jan 29;16:4. doi: 10.1186/s12014-019-9224-6

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Functional networks of differently abundant proteins in colon mucosa biopsies affected by ulcerative colitis compared to healthy controls. a Functional network of the 321 proteins with the strongest abundance decrease in ulcerative colitis compared to healthy tissue. Metabolic functions dominate this network, especially those located in the mitochondria. b Functional network of the 275 proteins with highest abundance increase in ulcerative colitis. Functions of the immune system characterize this network. Generated with ClueGO, Pathways: WikiPathways (updated: 10.03.2018), pV ≤ 0.01