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. 2019 Jan 28;38:38. doi: 10.1186/s13046-019-1046-x

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© The Author(s). 2019

, corrected publication 2021. Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — β-catenin silencing reversed the promotion effects of SPRY2 knockdown on EMT-associated migration and invasion of PDAC cells. a Wound healing assay was carried out to investigate the migratory ability of PANC-1 and SW1990 cells. b Transwell assay was applied to assess the migratory and invasive capacities of PANC-1 and SW1990 cells. c The protein expression of SPRY2, β-catenin, TCF4, E-cad and VIM were detected in PANC-1 and SW1990 cells by Western blot. *P < 0.05, **P < 0.01, ***P < 0.001. ns non-significant