. 2019 Jan 28;38:38. doi: 10.1186/s13046-019-1046-x

Table 2.

Association between FOXO3a expression and clinicopathological features in PDAC patients

Clinicopathological feature	Total	Expression of FOXO3a		P value
	Total	High	Low
	130	(n = 63, 48.5%)	(n = 67, 51.5%)
Age(y)
<60	80	36	44	0.413
≥60	50	27	23	0.413
Gender
Male	75	39	36	0.444
Female	55	24	31	0.444
Tumor location
Head	108	50	58	0.390
Body/tail	22	13	9	0.390
TNM stage (AJCC)
I	39	35	4	<0.001
II	78	27	51
III	7	1	6
IV	6	0	6
Tumor size (cm)
≤2 cm	9	5	4	0.739
>2 cm	121	58	63	0.739
Depth of invasion
T1, T2	57	40	17	<0.001
T3, T4	73	23	50	<0.001
Lymph node metastasis
N0 (Negative)	79	56	23	<0.001
N1 (Positive)	51	7	44	<0.001
Distant metastasis
M0	124	63	61	0.044
M1	6	0	6	0.044
Vascular invasion
No	102	51	51	0.648
Yes	28	12	16	0.648
Perineural invasion
No	117	59	58	0.292
Yes	13	4	9	0.292
Histologic grade
Well differentiation	18	14	4	<0.001
Moderate differentiation	67	42	25
Poor differentiation	45	7	38