Table 2.

Effects of fluid administration on hemodynamic parameters in fluid responders and non-responders

Hemodynamic variables	Pre VE	Post VE	p values R and NR baseline	p values Pre and postVE
CI (L/min/m2)
Responders	2.1 [2.0–2.2]	2.8 [2.5–3.4]	0.0006	0.0005
Non-responders	2.8 [2.4–2.9]	2.7 [2.4–2.9]		0.24
SVI (mL/m2)
Responders	24 [21–26]	38 [29–41]	0.001	0.0006
Non-responders	34 [28–40]	35 [28–41]		0.08
MAP (mmHg)
Responders	71 [64–76]	88 [80–94]	0.13	0.0005
Non-responders	77 [69–86]	81 [72–89]		0.003
SAP (mmHg)
Responders	106 [98–124]	132 [122–149]	0.23	<  0.0001
Non-responders	115 [106–126]	128 [113–140]		<  0.0001
HR (beats/min)
Responders	90 [83–92]	85 [79–88]	0.01	0.02
Non-responders	73 [63–87]	71 [64–82]		0.14
PPV (%)
Responders	8.2 [5.6–14.8]	7.0 [5.8–10.6]	0.94	0.04
Non-responders	9.8 [7.0–17.4]	5.1 [4.3–7.7]		0.007

Data presented as median (25th – 75th IQR) unless otherwise specified

IQR interquartile, R responders, NR non-responders, VE volume expansion, CI cardiac index, SVI stroke volume index, MAP mean arterial pressure, SAP systolic arterial pressure, HR heart rate, PPV pulse pressure variation, VE volume expansion