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. 2019 Jan 28;156:7. doi: 10.1186/s41065-019-0083-y

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — The mRNA expression of 16 hub genes in different tumor stage of TCGA patients. The stage III and stage IV were set high degree stage group and the stage I and stage II were set low degree stage group. The Wilcoxon test was done between the two groups. The genes whose P-value ranked from low to high were as follows: a COL6A3. b CDH11. c COL8A1. d NTM. e COL11A1. f MMP2. g BGN. h COL1A1. i COL5A1. j COL3A1. k PXDN. l THBS2. m COL1A2. n THY1. o AEBP1. p TGFB1I1. Except for the expression of TGFB1I1, others were significant in distinguishing low and high tumor stage (P-value< 0.05)