Correlation between the Anti-inflammatory Activity of Exosomes in the In Vitro Macrophage Assay and in the Mouse Model of LPS-Induced Inflammation
(A) Correlation of the reduction in secreted IL-6 in the macrophage assay with the reduction of IL-1β or IL-6 mRNA expression in the spleen of LPS-treated mice. (B) Correlation of the reduction in secreted IL-6 in the macrophage assay with the reduction of IL-1β or IL-6 in the spleen of LPS-treated mice. Pearson coefficient of determination (r2) and the value of probability, p, are shown for each analysis.