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. 2018 Dec 15;13:67–76. doi: 10.1016/j.omtm.2018.12.003

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© 2018 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Correlation between the Anti-inflammatory Activity of Exosomes in the In Vitro Macrophage Assay and in the Mouse Model of LPS-Induced Inflammation

(A) Correlation of the reduction in secreted IL-6 in the macrophage assay with the reduction of IL-1β or IL-6 mRNA expression in the spleen of LPS-treated mice. (B) Correlation of the reduction in secreted IL-6 in the macrophage assay with the reduction of IL-1β or IL-6 in the spleen of LPS-treated mice. Pearson coefficient of determination (r²) and the value of probability, p, are shown for each analysis.