Table 2.
Rate of underestimation of malignancy in 90 patients with 99 high-risk lesions detected on MRI-VAB
Histopathologic diagnosis | Lesion frequency | No. excised | Underestimation rate | Cancer at surgery |
ADH | 21 (21) | 16 | 4/21 (19) | 4 (DCIS) |
Lobular neoplasia | 36 (36) | 21 | 2/36 (6) | 2 (1 DCIS, 1 ILC) |
ALH | 22 (22) | 13 | 0/36 (0) | 0 |
LCIS | 6 (6) | 2 | 0/36 (0) | 0 |
ALH and LCIS | 8 (8) | 6 | 2/36 (6) | 2 (1 DCIS, 1 ILC) |
Radial scar | 11 (11) | 2 | 0/11 (0) | 0 |
Papillary lesion | 22 (22) | 9 | 0/22 (0) | 0 |
Flat epithelial atypia | 1 (1) | 0 | 0/1 (0) | 0 |
Atypia unspecified | 8 (8) | 5 | 0/8 (0) | 0 |
Mucocele-like lesion | 0 (0) | 0 | 0/0 (0) | 0 |
ADH, atypical ductal hyperplasia; ALH, atypical lobular hyperplasia; DCIS, ductal carcinoma in situ; ILC, invasive lobular carcinoma; LCIS,lobular carcinoma in situ; MRI-VAB,MRI-vacuum-assisted biopsy.
Numbers in parentheses are percentages.