Table 2.
Absolute and percentage bias in nodule sizing between readers
| Systematic error (95%-LoA) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Interreader nodule volume | Interreader nodule diameter | Intrareader nodule diameter | ||||||
| Nodule margins | Abs. (mm3) |
% | Abs. (mm) |
DBV (mm3) |
% | Abs. (mm) |
DBV (mm3) |
% |
| Smooth | 0.7 (±22.4) |
−0.1 (±21.4) |
−0.1a (±1.9) |
−6.2 (±146.2) |
−0.7 (±83.3) |
0.0a
(±1.4) |
2.8 (±90.0) |
−0.1 (±71.0) |
| Lobulated | 1.0 (±23.8) |
−0.3 (±18.1) |
−0.2a (±2.0) |
−29.6a
(±191.7) |
−6.6 (±86.0) |
0.2a
(±1.5) |
21.6a
(±150.5) |
−6.6a
(±66.4) |
| Spiculated | 4.8 (±49.9) |
−1.4 (±28.2) |
0.0a
(±3.5) |
−28.1 (±410.4) |
3.9 (±122.1) |
0.6a
(±2.4) |
64.4a
(±278.0) |
3.9a
(±83.9) |
| Irregular | 0.7 (±61.3) |
0.2 (±27.0) |
0.5a
(±4.5) |
77.5a
(±1100.0) |
15.9 (±122.5) | 0.4a
(±2.9) |
89.7a
(±705.8) |
15.9 (±84.9) |
| Total (n = 100) | −1.1 (±42.3) |
−0.4 (±23.7) |
0.0a
(±3.2) |
3.4 (±602.3) |
3.1 (±106) |
0.3a
(±2.2) |
44.6a
(±393.2) |
10.5 (±78.0) |
95%-LoA, 95% limits of agreement; Abs, absolute systematic error; DBV, diameter based volume.
% symbol denotes relative systematic error for volume and diameter-based volume.
Number in brackets is 95%-LoA, bold 95%-LoA exceeds the growth cut-off of 25% or 1.5 mm.
a
Significant difference p < 0.05.